Epilepsy and Migraine Could Have A Shared Genetic Link BBC News

http://www.bbc.co.uk/news/health-20908903

Some of you may have seen this already but the BBC have reported on Epilepsy and Migraine may have a shared genetic link.

The study was done by Colombia University New York and show a higher incidence of Migraine in relatives of people closely related with epilepsy.

To some the idea that epilepsy and migraine are related is not new, but this is an interesting study.

Thanks for passing it on mum!

 

asdresearchinitiative very interesting articles on autism and epilepsy also neurological research.

asdresearchinitiative

Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex.

http://www.ncbi.nlm.nih.gov/pubmed/23250422

Impairment of reciprocal social interaction is a core symptom of autism spectrum disorder.

Genetic disorders frequently accompany autism spectrum disorder, such as tuberous sclerosis complex caused by haploinsufficiency of the TSC1 and TSC2 genes. Accumulating evidence implicates a relationship between autism spectrum disorder and signal transduction that involves tuberous sclerosis complex 1, tuberous sclerosis complex 2 and mammalian target of rapamycin.

Here we show behavioural abnormalities relevant to autism spectrum disorder and their recovery by the mammalian target of rapamycin inhibitor rapamycin in mouse models of tuberous sclerosis complex. In Tsc2(+/-) mice, we find enhanced transcription of multiple genes involved in mammalian target of rapamycin signalling, which is dependent on activated mammalian target of rapamycin signalling with a minimal influence of Akt.

The findings indicate a crucial role of mammalian target of rapamycin signalling in deficient social…

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